The Swiss ones develop new nano-magnetic particles to clean blood
Zurich, Switzerland, researchers are to develop the nano-magnetic particles to look at turned ahead to far the potentially harmful ingredients from blood. This technique can be employed for the treatment of human poisoning, the infections of blood and certain cancers.
Work comprises magnetic clothing of nanoparticles coated by carbon, covers as of the their antibodies against the specific molecules. The researchers think these elements, such as protein which lead easily to the ignition: interleukin and some metals of poison, such as the wire, removed blood. In blood after having added the nano-magnetic grains, and then leave blood in the machine of dialysis and by the machine still, the researchers can filter outside the nondesired components.
�the Nano-magnetic particles can capture the composition out of target. The magnetic particles before using the re-use, should accumulate these magnetic particles of toxic substances with a magnetic separator in a deposit, so that they are separated from the circulatory system of blood.� Inge Herrmann explained which is a chemical engineer of university of Zurich, now undertaking the study.
In accordance with February 2011 a number of magazine of dialysis and �transplantation of nephrology� published the results of the study, researchers can remove 75% of digoxin of a sieve of blood, which is a drug of heart, catch of the high amounts is representing a danger to the life. After a half an hour process of displacement, magnetic grains can be removed up to 90% of digoxin.
Particular note, the researchers must prove that the magnetic particles on the human body itself is not-poison and does not affect the capacity of the coagulation of blood. The results early were promising. Published in 2011, a paper on �Nanomedicine�, the team of Hermann proved that the magnetic grains did not damage the cell, it would not increase the capacity of coagulation. They is two critical big steps of safety. In October, the american company of the anaesthetists annual meeting, Hermann presented the exposure of data which part of the magnetic particles is absorbed by two immunized cells, monocytes and macrophages. This proves an important principle, any future application of the results can be employed to treat serious infections.
Now, Hermann and his colleagues suffer from the sepsis in the mice to undertake a technical study. Sepsis is a serious infection of blood, the combination of a great number of damaged immunized cells are their signs. In the United States, approximately 100 million people suffers from the disease. Jon Dobson is a biomedical engineer of university of Florida, he said that the detoxication is �very interesting applications �of nanotechnology. Its team employs the magnetic nanoparticles as remote-control, to operate the activity of cells, such as the differentiation of cells of stem. �Chemical Method, once it is difficult to stop the beginnings of process it. With magnetic technology, you can order the contact �STOP� of the heart.�
The Swiss team developed the method, her use potential can be increased with other diseases, field septic, including leukaemia, Dobson said. For example, of the nano-magnetic particles can be conceived to match and of the cells of leukaemia, and then guide them to excrete, reducing of this fact the risk of metastasis of tumour.
O. Thompson Mefford is an expert as regards nanotechnology of university of Clemson. He said that this achievement was very attractive. He specified that the human body was an environment strongly of oxidation, and it iron oxide will weaken magnetic materials. The Swiss team gave the magnetic particles with a layer of carbon clothing, to prevent corrosion. But it always specified, the technology of survival remains to see. �Made a cycle for a long time, it has there no immunoreaction and not in the groups between the magnetic particles, they are still true challenge.�
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